People react to drugs differently, observe their varying effectiveness and suffer from different side effects. The main cause of many of such differences are genetic variations. Through the analysis of the genes which affect the processing of drugs in the system, the safety of their use and their bio-availability in the system, it is possible to adjust the treatment to a specific patient's needs, individualize their drug doses, and minimize the risk of side effects.

The main goal of pharmacogenomics is to provide support in choosing individual treatment strategies, which involve selecting those drugs which are most likely to deliver therapeutic benefits, and their correct dosage.

For whom?

Pharmacological tests are carried out in order to determine the potential response of the organism to the medication used in therapy. The results of the tests can provide additional information for the physician overseeing the treatment.

Recommendation for pharmacological profile tests:

Report Subjects in the Pharmacogenomics Section

Hypercholesterolemia Treatment

Risk of Swelling and Rash after Using Non-Steroid Anti-Inflammatory Drugs

Genetically Conditioned Reaction to Anti-HCV Treatment

Genetically Conditioned Reaction to Antidepressants

Genetically Conditioned Reaction to Using Citalopram

Genetically Conditioned Reaction to Treating HCV Infection with Protease Inhibitors

Genetically Conditioned Reaction to Hepatitis B Vaccine

Asthma - Reaction to Inhaling Corticosteroids

Asthma - Reaction towards Bronchodilators

Lymphoblastic Leukemia - Reaction towards Treatment

Cardiovascular Diseases - Reaction towards Fenofibrate

Customer Benefits

The customer will get a set of data which will enable them to add the genetic polymorphism profile conditioning their reactions to drugs to other previously known factors which modify the way drugs work, such as age, gender, coexisting diseases, drug interactions. This additional information may be used as a guideline by the physician overseeing the treatment in order to:

increase the effectiveness of drug therapy
eliminate side effects of drugs related to patients' slow metabolism (poor metabolizers)
reduce subtherapeutic concentration of a drug after using standard doses (extensive metabolizers)
choose alternative methods of monitoring drug concentration