People react to drugs differently, observe their varying effectiveness and suffer from different side effects. The main cause of many of such differences are genetic variations. Through the analysis of the genes which affect the processing of drugs in the system, the safety of their use and their bio-availability in the system, it is possible to adjust the treatment to a specific patient's needs, individualize their drug doses, and minimize the risk of side effects.
The main goal of pharmacogenomics is to provide support in choosing individual treatment strategies, which involve selecting those drugs which are most likely to deliver therapeutic benefits, and their correct dosage.
Pharmacological tests are carried out in order to determine the potential response of the organism to the medication used in therapy. The results of the tests can provide additional information for the physician overseeing the treatment.
Recommendation for pharmacological profile tests:
Polymorphic drug metabolism
Low therapeutic index
Unexpected treatment result
Too low or too high concentration of a drug in a serum
Risk of Swelling and Rash after Using Non-Steroid Anti-Inflammatory Drugs
Genetically Conditioned Reaction to Anti-HCV Treatment
Genetically Conditioned Reaction to Antidepressants
Genetically Conditioned Reaction to Using Citalopram
Genetically Conditioned Reaction to Treating HCV Infection with Protease Inhibitors
Genetically Conditioned Reaction to Hepatitis B Vaccine
Asthma - Reaction to Inhaling Corticosteroids
Asthma - Reaction towards Bronchodilators
Lymphoblastic Leukemia - Reaction towards Treatment
Cardiovascular Diseases - Reaction towards Fenofibrate
The customer will get a set of data which will enable them to add the genetic polymorphism profile conditioning their reactions to drugs to other previously known factors which modify the way drugs work, such as age, gender, coexisting diseases, drug interactions. This additional information may be used as a guideline by the physician overseeing the treatment in order to: